SEATTLE, Wash. and VANCOUVER, British Columbia, June 21, 2019 — Achieve Life Sciences, Inc. (Nasdaq: ACHV), a clinical-stage pharmaceutical company focused on nicotine addiction, today announced that an abstract featuring data from the Phase 2b ORCA-1 trial has been accepted for oral presentation at the SRNT-E Annual Conference, to be held in Oslo, September 12-14, 2019.

The abstract “A Multicenter, Double-blind, Randomized, Placebo-controlled Phase 2b Trial of Cytisinicline in Adult Smokers” and oral presentation will include updated cytisinicline data from the recently completed ORCA-1 trial.

As recently reported, the 254-subject ORCA-1 dose-selection trial of cytisinicline demonstrated a statistically significant improvement in quit rates for a simplified 3.0 mg, three times daily dose administered over a 25-day treatment period. In the trial, adherence to study treatment was greater than 98.5% across all arms and cytisinicline was well-tolerated with no serious adverse events reported.

Additional information on cytisinicline and the ORCA program can be found at www.achievelifesciences.com and www.orcaprogram.com.

About Cytisinicline
Tobacco use is currently the leading cause of preventable death and is responsible for nearly seven million