SEATTLE, Wash. and VANCOUVER, British Columbia, September 5, 2019 – – Achieve Life Sciences, Inc. (Nasdaq: ACHV), a clinical-stage pharmaceutical company committed to the global development and commercialization of cytisinicline for smoking cessation, today announced the Company will host its first investor day on Friday, September 20, 2019 in New York City.

The event will include an updated data presentation by the primary investigator of the Phase 2b ORCA-1 trial of cytisinicline.  It will also feature a panel discussion moderated by leading healthcare analysts, Michael Higgins from Ladenburg Thalmann and Jason McCarthy from Maxim Group, with participation from four esteemed medical experts in the field of smoking cessation.

In June of 2019, Achieve Life Sciences announced statistically significant, topline results from its 254-subject, Phase 2b ORCA-1 dose-selection trial of cytisinicline for smoking cessation.  The outcome of the trial has led to the selection of 3.0 mg, three times daily (TID) dosing for future Phase 3 development.  Cytisinicline treatment demonstrated significant improvements across all treatment arms in both reduction in cigarettes smoked and abstinence rates compared to placebo.  The most impressive results were observed in the 3 mg TID treatment arm which demonstrated a 54% abstinence rate at week 4, compared to 16% for placebo (p < 0.0001) and a continuous abstinence rate, weeks 5 through 8, of 30% for cytisinicline compared to 8%