Home

Join us in redefining the future of

nicotine dependence

 

We are a late-stage specialty pharmaceutical company dedicated to tackling the global nicotine dependence epidemic by advancing cytisinicline.

If approved, cytisinicline has the potential to become the first new FDA-approved treatment option in 20 years.

25M

Smokers in the US 1

18M

E-Cigs in the US 1

Nicotine dependence is a serious medical issue that demands a medical solution

The harms associated with smoking are well established, increasing the risk of COPD, cardiovascular disease, cancer, and other serious conditions.

While over half attempt to quit smoking each year, fewer than 10% succeed.2 The toll is staggering – lost lives and over $600 billion in annual smoking-related healthcare costs.14

A more effective treatment is critical to addressing this widespread public health crisis.

8M

Worldwide Deaths Annually4

16M

Americans Live with Smoking- Related Disease5

Introducing

Cytisinicline

demonstrated in clinical trials to provide favorable odds of quitting6,7

focused on precision targeting of nicotine receptors

In two recent trials, cytisinicline has been shown to effectively help even highly dependent smokers stop smoking.6,7 Cytisinicline binds to the same receptors as nicotine to reduce both withdrawal symptoms and satisfaction associated with smoking.8 And since it doesn’t bind as strongly to certain receptors, it is believed to have less potential to cause side effects — including nausea and vomiting.

Smoking cessation phase 3 trial results

vaping cessation phase 2 trial results

cytisinicline development program

Latest News

 

Achieve Life Sciences Strengthens Board and Commercial Leadership with Three Senior Appointments from Team Previously at Verona Pharma

Christopher Martin joins the Board of Directors, with Mark Zappia and Jim Willis joining as Senior Vice President of Com

Read More

Achieve Life Sciences Reports First Quarter 2026 Financial Results and Provides Business Updates

Closed Private Placement of Up to $354 Million, Including $180 Million Upfront and $174 Million in Milestone-Driven Warr

Read More

Achieve Life Sciences to Announce First Quarter 2026 Financial Results and Host Conference Call and Webcast on May 12, 2026

SEATTLE and VANCOUVER, British Columbia, May 5, 2026 (GLOBE NEWSWIRE) — Achieve Life Sciences, Inc. (Nasdaq: ACHV)

Read More

Achieve Life Sciences Announces Up to $354 Million Private Placement

$180 Million Financing Upfront with Up to an Additional $174 Million from Warrants Exercisable Within 20 Days of FDA App

Read More

WE CAN’T HELP BUT
BELIEVE

And we’re looking for others, like us, who believe we can bring an end to this fight. Will you join us?

  • US Headquarters
  • 22722 29th Dr SE, Suite 100
  • Bothell, WA 98021
  • Phone: (425) 686-1500
  • Vancouver Office
  • 1040 W Georgia Street, Suite 1030
  • Vancouver, BC V6E 4H1